What is an Alpha 2 Macroglobulin (A2M) Injection?
A2M injections are a cutting-edge new treatment for osteoarthritis and other painful orthopedic conditions. A2M is a molecule that occurs naturally in your bloodstream and when injected into the osteoarthritic or painful area, begins to promote healing.
Made in the liver, Alpha 2 Macroglobulin (A2M) protects your tissues and boosts natural healing by binding to destructive enzymes that cause cartilage decay and osteoarthritis.
These enzymes are called proteases. Proteases perform an essential metabolic function: breaking down proteins. However, they can also eat away at your cartilaginous tissue, especially if that tissue has been damaged by a traumatic injury or overuse. As the cartilage degenerates, the joint becomes inflamed, leading to chronic pain and stiffness.
A2M molecules inhibit proteases by binding to them, rendering them harmless and allowing them to be flushed naturally from your body. But the molecule itself is large and complex. It travels easily through the bloodstream, but not through your “avascular” cartilage – meaning it has no veins.
A2M is an effective treatment for many conditions, including:
How does A2M Therapy Work?
An A2M injection deposits a rich supply of A2M directly into the injured area. The molecules quickly get to work, binding to and removing destructive enzymes from your joint tissue.
At your appointment, your blood will be drawn and spun in a centrifuge to separate it into red and yellow plasma. The yellow plasma, concentrated 6X with A2M molecules, will be re-injected into your joint.
The procedure is minimally-invasive, and not painful. Most patients tell us they feel an improvement in symptoms and mobility on the very same day. The anti-inflammatory effects may last for several months, depending on your circumstances.
Early, regular treatments can relieve pain, promote tissue growth, and slow or stop the progress of joint degeneration. It can even prevent or limit the onset of post-traumatic osteoarthritis.
Who is a Good Candidate for A2M Injections?
A2M is a safe and effective treatment many joint pain conditions, including:
- Osteoarthritis (Knee arthritis, Hip arthritis)
- Joint injuries (Shoulder, Knee, Elbow, Rotator cuff)
- Labral Tear
- Torn meniscus
- Spinal injuries (Neck, Back)
- Lumbar and sacral osteoarthritis
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- Sciatica (Lumbar radiculopathy)
- Herniated disc (Slipped disc, Disc displacement)
- Degenerative disc disease
A simple biomarker test can tell if you’re a good candidate for this A2M injections.
Nuvo Spine specializes in minimally-invasive, non-surgical, innovative techniques in pain management. Our board-certified orthopedic pain specialist will assess your condition and design your individualized pain management plan. If you’re looking for long-lasting pain relief that protects your joints and staves off osteoarthritis, call our offices today.